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NEET-UG Biology · Class 11

Passing the signal at a synapse — NEET & JEE Questions

Passing the signal at a synapse is a topic in Neural Control and Coordination, a Class 11 Biology chapter of the NEET-UG syllabus. TestBudy holds 14 published NEET-UG questions on Passing the signal at a synapse, each with the marking scheme of the real paper. The ideas it examines include Electrical vs chemical synapse differences, Steps in releasing a neurotransmitter.

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Key formulas and concepts

The ideas Passing the signal at a synapse is examined on, as they are tagged in the syllabus tree.

  • Electrical vs chemical synapse differences
  • Steps in releasing a neurotransmitter

Passing the signal at a synapse MCQs with solutions

10 of the 14 published questions on this topic, exactly as they appear in a test. Answers and worked solutions come with your result rather than on this page.

  1. Question 1 · difficulty L1 · recall

    A typical chemical synapse conducts in one direction mainly because:

    • A. myelin covers the cleft
    • B. both sides release identical transmitters simultaneously
    • C. neurotransmitter is released presynaptically and receptors are postsynaptic
    • D. ions cannot cross any membrane
  2. Question 2 · difficulty L1 · recall

    What is released from a presynaptic terminal at a chemical synapse?

    • A. Neurotransmitter
    • B. Myelin protein
    • C. Cerebrospinal fluid
    • D. Nissl granules
  3. Question 3 · difficulty L1 · recall

    What is the narrow gap between two cells at a chemical synapse called?

    • A. Node of Ranvier
    • B. Synaptic cleft
    • C. Central canal
    • D. Axon hillock
  4. Question 4 · difficulty L2 · understanding

    Why is transmission at a typical chemical synapse mainly one-way?

    • A. The cleft allows current only forward
    • B. Both cells release identical transmitters
    • C. Release machinery is presynaptic and receptors are postsynaptic
    • D. Postsynaptic membranes lack ion channels
  5. Question 5 · difficulty L2 · understanding

    What normally triggers synaptic vesicles to fuse with the presynaptic membrane?

    • A. Closure of voltage-gated channels
    • B. Potassium entry into the postsynaptic cell
    • C. Breakdown of the myelin sheath
    • D. Calcium entry into the presynaptic terminal
  6. Question 6 · difficulty L2 · understanding

    At a chemical synapse, the neurotransmitters are stored in synaptic vesicles located in the

    • A. dendrites of the post-synaptic neuron
    • B. synaptic cleft
    • C. axon terminal of the pre-synaptic neuron
    • D. cell body of the post-synaptic neuron
  7. Question 7 · difficulty L3 · application

    A toxin prevents synaptic vesicles from fusing with the presynaptic membrane. Which event fails first?

    • A. Neurotransmitter release
    • B. Axonal action-potential propagation
    • C. Myelin formation
    • D. DNA replication in the neuron
  8. Question 8 · difficulty L3 · application

    A neurotransmitter opens sodium-permeable channels on the postsynaptic membrane. What is the immediate effect?

    • A. Postsynaptic hyperpolarisation
    • B. Postsynaptic depolarisation
    • C. Permanent loss of resting potential
    • D. Formation of new myelin
  9. Question 9 · difficulty L3 · application

    Why is rapid removal of neurotransmitter from the synaptic cleft important?

    • A. It converts the synapse into an electrical junction
    • B. It keeps receptors permanently active
    • C. It terminates the signal and allows the synapse to reset
    • D. It prevents future vesicle production
  10. Question 10 · difficulty L3 · application

    A nerve impulse reaches the axon terminal of a neuron whose synapse with the next neuron has a fluid-filled gap. Arrange the events that follow in the correct order: (1) neurotransmitter binds to receptors on the post-synaptic membrane; (2) synaptic vesicles fuse with the pre-synaptic membrane; (3) ion channels open, generating a new potential; (4) neurotransmitter diffuses across the cleft.

    • A. 4-2-1-3
    • B. 1-2-4-3
    • C. 2-1-4-3
    • D. 2-4-1-3

Common mistakes in Passing the signal at a synapse

Recorded against questions in this topic that are not shown above, so none of these points at an answer you can see on this page.

  • Assuming any excitatory input automatically generates an action potential.
  • Looking only at postsynaptic receptors and overlooking the presynaptic release mechanism.
  • Assigns the neurotransmitter to the electrical synapse, or the cleft to the electrical one.
  • Believes the neurotransmitter itself carries the signal into the post-synaptic cell.

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