Transgenic animals — NEET & JEE Questions

Question 1 · difficulty L1 · recall

What is a transgenic animal?

• A. An animal with no DNA
• B. Any animal produced by selective breeding
• C. An animal engineered to carry a foreign gene
• D. Any cloned animal regardless of its genes

Question 2 · difficulty L2 · understanding

Why are transgenic animals useful for studying gene function?

• A. They cannot pass genes to offspring
• B. They eliminate the need for controls
• C. Every inserted gene produces the same phenotype
• D. Gene changes can reveal effects on physiology

Question 3 · difficulty L2 · understanding

A transgenic animal is one that

• A. carries an introduced foreign or modified gene in its genome
• B. has been fed genetically modified food
• C. has undergone only natural mutation
• D. contains no DNA

Question 4 · difficulty L2 · understanding

One important use of transgenic animals is to

• A. study gene function and model human disease
• B. replace every clinical trial automatically
• C. eliminate the need for biological research
• D. prevent inheritance of genes

Question 5 · difficulty L3 · understanding

The human protein named $\boldsymbol{\alpha}$-1-antitrypsin, obtained from transgenic animals, is used for the treatment of $\_\_\_\_$ .

• A. Emphysema
• B. Alzheimer's disease
• C. Rheumatoid arthritis
• D. Cystic fibrosis

Question 6 · difficulty L3 · understanding

Milk of transgenic ‘Cow Rosie’ was nutritionally more balanced product for human babies than natural cow milk because it contained:

• A. Human enzyme Adenosine Deaminase (ADA)
• B. Human protein $$\alpha$$-1-antitrypsin
• C. Human alpha-lactalbumin
• D. Human insulin-like growth factor

Question 7 · difficulty L3 · application

A transgenic mouse develops symptoms similar to a human genetic disease. What is a major research use of this model?

• A. Study disease mechanisms and potential treatments
• B. Replacing every human clinical study
• C. Producing methane
• D. Measure population allele frequencies across multiple human generations

Question 8 · difficulty L3 · application

A mouse is engineered to carry a mutant human gene associated with a disease. What is the most direct research use?

• A. Studying disease development and testing possible interventions
• B. Increasing crop yield
• C. Measuring soil nitrogen
• D. Producing bacterial spores

Question 9 · difficulty L4 · analysis

Why might a transgenic animal be engineered to produce a human therapeutic protein in its milk?

• A. The protein automatically changes the animal into a human
• B. Milk can provide the therapeutic protein
• C. Milk prevents gene expression
• D. The animal no longer needs the inserted gene

Question 10 · difficulty L4 · application

Why must a introduced transgene be present in germ-line cells if a stable transgenic animal line is to be established?

• A. So the transgene can be inherited by offspring
• B. So the animal immediately becomes sterile
• C. So every somatic cell loses its chromosomes
• D. So the transgene remains only in one tissue