Immunity - innate and acquired — NEET & JEE Questions

Question 1 · difficulty L1 · recall

Which type of immunity is present from birth and acts without prior exposure to a specific pathogen?

• A. Innate immunity
• B. Acquired immunity only
• C. Artificial passive immunity only
• D. Vaccination

Question 2 · difficulty L2 · understanding

Which of the following type of immunity is present at the time of birth and is a non-specific type of defence in the human body?

• A. Cell-mediated Immunity
• B. Humoral Immunity
• C. Acquired Immunity
• D. Innate Immunity

Question 3 · difficulty L2 · understanding

Which defence is part of innate immunity?

• A. Intact skin as a physical barrier
• B. Antigen-specific memory cells
• C. A secondary antibody response
• D. Clonal expansion after vaccination

Question 4 · difficulty L2 · understanding

Acquired immunity differs from innate immunity because acquired immunity

• A. is antigen-specific and can generate immunological memory
• B. is always present unchanged from birth
• C. has no lymphocyte involvement
• D. cannot improve after exposure

Question 5 · difficulty L3 · understanding

Match List-I with List-II. List - I List - II (A) Cytokine barriers (I) Mucus coating of respiratory tract (B) Cellular barriers (II) Interferons (C) Physiological barriers (III) Neutrophils and Macrophages (D) Physical barriers (IV) Tears and Saliva Choose the correct answer from the options given below :

• A. (A)-(II), (B)-(III), (C)-(IV), (D)-(I)
• B. (A)-(III), (B)-(I), (C)-(IV), (D)-(II)
• C. (A)-(III), (B)-(I), (C)-(II), (D)-(IV)
• D. (A)-(II), (B)-(III), (C)-(I), (D)-(IV)

Question 6 · difficulty L3 · understanding

Match List - I with List - II : List - I List - II (a) Cellular barrier (i) Interferons (b) Cytokine barrier (ii) Mucus (c) Physical barrier (iii) Neutrophils (d) Physiological barrier (iv) HCl in gastric juice Choose the correct answer from the options given below :

• A. (a) - (iii), (b) - (i), (c) - (ii), (d) - (iv)
• B. (a) - (ii), (b) - (iii), (c) - (iv), (d) - (i)
• C. (a) - (ii), (b) - (iii), (c) - (i), (d) - (iv)
• D. (a) - (iii), (b) - (iv), (c) - (ii), (d) - (i)

Question 7 · difficulty L3 · application

What distinguishes acquired immunity from innate immunity most clearly?

• A. Presence from birth only
• B. Specificity plus memory
• C. Absence of lymphocytes
• D. Complete lack of specificity

Question 8 · difficulty L3 · understanding

Identify the statement that is NOT correct.

• A. Antigen binding site is located at C-terminal region of antibody molecules.
• B. Constant region of heavy and light chains are located at C-terminus of antibody molecules
• C. Each antibody has two light and two heavy chains.
• D. The heavy and light chains are held together by disulfide bonds.

Question 9 · difficulty L3 · understanding

Match List I with List II : List - I List - II (A) B-Lymphocytes (I) Passive immunity (B) Interferons (II) Cell mediated immunity (C) T-Lymphocytes (III) Produce an army of proteins in response to pathogens (D) Colostrum (IV) Innate immunity Choose the correct answer from the options given below :

• A. A-I, B-IV, C-II, D-III
• B. A-IV, B-II, C-III, D-I
• C. A-III, B-IV, C-II, D-I
• D. A-II, B-IV, C-I, D-III

Question 10 · difficulty L3 · understanding

Which of the following reasons is mainly responsible for graft rejection in transplantation of organs?

• A. Cell-mediated response
• B. Inability of recipient to differentiate between ‘self’ and ‘non-self’ tissues/cells
• C. Humoral immune response only
• D. Auto-immune response