Allergies, autoimmunity and the lymphoid organs — NEET & JEE Questions

Question 1 · difficulty L1 · recall

A primary lymphoid organ in humans is the

• A. thymus
• B. spleen
• C. lymph node
• D. tonsil

Question 2 · difficulty L2 · understanding

After maturation, in primary lymphoid organs, the lymphocytes migrate for interaction with antigens to secondary lymphoid organ(s) / tissue(s) like A. thymus B. bone marrow C. spleen D. Iymph nodes E. Peyer's patches Choose the correct answer from the options given below

• A. E, A, B only
• B. C, D, E only
• C. B, C, D only
• D. A, B, C only

Question 3 · difficulty L2 · understanding

What is an allergy?

• A. A bacterial infection of lymph nodes
• B. A complete absence of immune activity
• C. Excess response to a harmless antigen
• D. Failure of blood clotting

Question 4 · difficulty L2 · understanding

An allergy is best described as

• A. an exaggerated immune response to an otherwise usually harmless antigen
• B. complete absence of immune response
• C. an immune attack only against self tissues
• D. normal tolerance to pollen

Question 5 · difficulty L3 · understanding

Given below are two statements : Statement I : Bone marrow is the main lymphoid organ where all blood cells including lymphocytes are produced. Statement II : Both bone marrow and thymus provide micro environments for the development and maturation of T-lymphocytes. In the light of above statements, choose the most appropriate answer from the options given below

• A. Both Statement I and Statement II are correct.
• B. Both Statement I and Statement II are incorrect.
• C. Statement I is correct but Statement II is incorrect.
• D. Statement I is incorrect but Statement II is correct.

Question 6 · difficulty L3 · application

Why is the thymus especially important during early life?

• A. It synthesises antibodies directly
• B. It produces red blood cells throughout adult life
• C. It stores digestive enzymes
• D. It supports maturation of T lymphocytes

Question 7 · difficulty L3 · understanding

Which of the following are Autoimmune disorders? A. Myasthenia gravis B. Rheumatoid arthritis C. Gout D. Muscular dystrophy E. Systemic Lupus Erythematosus (SLE) Choose the most appropriate answer from the options given below:

• A. A, B & D only
• B. A, B & E only
• C. B, C & E only
• D. C, D & E only

Question 8 · difficulty L3 · understanding

Given below are two statements: Statement I : Autoimmune disorder is a condition where body defense mechanism recognizes its own cells as foreign bodies. Statement II : Rheumatoid arthritis is a condition where body does not attack self cells. In the light of the above statements, choose the most appropriate answer from the options given below :

• A. Both Statement I and Statement II are correct
• B. Both Statement I and Statement II are incorrect
• C. Statement I is correct but Statement II is incorrect
• D. Statement I is incorrect but Statement II is correct

Question 9 · difficulty L4 · analysis

In an autoimmune disorder, what has gone wrong with immune recognition?

• A. The immune system attacks self-components
• B. All antigens are ignored
• C. Only pathogens are attacked more efficiently
• D. Antibodies can no longer bind anything

Question 10 · difficulty L4 · application

A patient's immune system produces responses against the patient's own tissues. This condition is most consistent with

• A. autoimmunity
• B. allergy
• C. passive immunisation
• D. immunological tolerance